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Holly Larue Frizzelle, 3, turns away from the camera outside her home in Wilmington. During the phase known as Delayed Intensification Larue became agitated by having her photo taken. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.